Identical twins and the differences between their cells
Genetic changes can arise as an embryo's cells divide and enter different cell lineages. Comparing sampled DNA can reveal differences between identical twins, while differences in gene activity and experience offer separate parts of their histories.
Questions you could explore
- What could DNA from one tissue tell you, and what would it leave unknown about the rest of the body?
- How could mutations arising after the embryo divides lead to differences between twins?
Start reading
- Nature Genetics / Jónsson and colleagues; paper mirrored by GwernDifferences between Germline Genomes of Monozygotic Twins
Investigates genetic changes arising during early development, showing why a shared origin need not mean identical sampled DNA.
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