Why can harmless pollen set off an immune alarm?
Pollen does not need to be a dangerous invader to trigger sneezing and watery eyes. In an allergic response to ragweed pollen, earlier exposure can leave IgE antibodies attached to mast cells, ready to help trigger a reaction when the allergen returns.
Questions you could explore
- What changes between sensitization and a later exposure?
- How do an allergen-specific response and the immediate chemicals released during a reaction fit together?
Start reading
- OpenStax, Biology 2e42.4 Disruptions in the Immune System
Uses ragweed pollen to explain sensitization, IgE, mast cells, and chemical signals behind an allergic response.
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